MDDEfficacy
May 2025
Scientific Evidence
In completed clinical trials, delivery of SAINT® therapy for MDD has resulted in a significant reduction in depressive symptoms following the five-day treatment protocol.
BipolarEfficacy
November 2024
Fast depressive symptoms improvement in bipolar I disorder after Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT): A two-site feasibility and safety open-label trial
Journal of Affective Disorders | Volume 365, Pages 359-363
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Kevin Li, Amy Bichlmeier, Caitlin DuPont, Jennifer E. Siegel-Ramsay, Alexa Comfort, Erin Logue, Katy H. Stimpson, Brandon Bentzley, Nolan Williams, Irving Reti, Jorge Almeida, Peter Zandi
MDDOther
October 2024
Early differences in lassitude predicts outcomes in Stanford Neuromodulation Therapy for difficult to treat depression
npj Mental Health Research | Volume 3, Article 49
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David Benrimoh, Azeezat Azeez, Jean-Marie Batail, Xiaoqian Xiao, Derrick Buchanan, Igor D. Bandeira, Andrew Geoly, Yaakov Keynan, Ian H. Kratter & Nolan R. Williams
MDDDurability
October 2024
Durability of clinical benefit with Stanford Neuromodulation Therapy (SNT) in treatment-resistant depression: assessment of sustained remission and response following index treatment
Neuromodec Journal | Volume 4, Issue 2
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Andrew D. Geoly, M.S; Katy H. Stimpson, Psy.D; Flint M. Espil, Ph.D; Brandon S. Bentzley, M.D Ph.D; Nolan R. Williams, M.D
MDDNeuroimaging
July 2024
Increased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham- controlled trial
npj Mental Health Research | Volume 3, Article 35
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Niharika Gajawelli, Andrew D. Geoly, Jean-Marie Batail, Xiaoqian Xiao, Adi Maron-Katz, Eleanor Cole, Azeezat Azeez, Ian H. Kratter, Manish Saggar & Nolan R. Williams
MDDContinuation
May 2024
An Open Label Pilot Trial to Assess the Feasibility of Using the Magnus Neuromodulation System with Stanford Accelerated Intelligent Neuromodulation Therapy (SAINTR) as a Personalized Continuation Therapy for Depression
OSF
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Katy H Stimpson, TJ Ford, Adi Maron-Katz, Michael Feyder, Danielle D DeSouza, David Carreon, Eleanor J Cole, Brandon S Bentzley
BipolarEfficacy
March 2024
Pilot study of stanford neuromodulation therapy (SNT) for bipolar depression
Brain Stimulation | Volume 17, Issue 2, 321-323
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Kristin S. Raj, Andrew D. Geoly, Clive Veerapal, Mia Gholmieh, Pouya Toosi, Flint M. Espil, Jean-Marie Batail, Ian H. Kratter, Nolan R. Williams
MDDDurability
January 2024
Sustained Efficacy of Stanford Neuromodulation Therapy (SNT) in Open-Label Repeated Treatment
American Journal of Psychiatry | Volume 181, Number 1
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Andrew D. Geoly, M.S., Ian H. Kratter, M.D., Ph.D., Pouya Toosi, M.D., Eleanor J. Cole, Ph.D., Gregory L. Sahlem, M.D., and Nolan R. Williams, M.D.
MDDContinuation
January 2024
12 Months Sustained Remission from Depression using Personalized Continuation Therapy with SAINT®
Magnus Medical
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Katy H Stimpson, TJ Ford, Adi Maron-Katz, Michael Feyder, Danielle D DeSouza, David Carreon, Eleanor J Cole, Brandon S Bentzley
MDDOther
November 2023
An Avenue for Optimization of Theta Burst Stimulation Protocols? Comments on the FOUR-D Randomized Noninferiority Clinical Trial
American Journal of Psychiatry | Volume 181, Number 1
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Jean-Marie V. Batail, M.D., Ph.D., Michael T. Feyder, Ph.D., Brandon S. Bentzley, M.D., Ph.D., Nolan R. Williams, M.D.
MDDNeuroimaging
July 2023
Network effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial
Nature Translational Psychiatry | 13, 240
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Jean-Marie Batail, Xiaoqian Xiao, Azeezat Azeez, Claudia Tischler, Ian H. Kratter, James H. Bishop, Manish Saggar, Nolan R. Williams
MDDNeuroimaging
May 2023
Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression
PNAS | Volume 120, Number 21
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Anish Mitra, Marcus E. Raichle, Andrew D. Geoly, Ian H. Kratter, and Nolan R. Williams
MDDEfficacy
October 2021
Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial
American Journal of Psychiatry | Volume 179, Issue 2
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Eleanor J. Cole, Ph.D., Angela L. Phillips, Ph.D., Brandon S. Bentzley, M.D., Ph.D., Katy H. Stimpson, B.S., Romina Nejad, M.S., Fahim Barmak, M.D., Clive Veerapal, B.S., Naushaba Khan, B.S., Kirsten Cherian, Ph.D., Emily Felber, M.S., Randi Brown, M.S., Elizabeth Choi, M.S., Sinead King, Ph.D., Heather Pankow, B.S., James H. Bishop, Ph.D., Azeezat Azeez, Ph.D., John Coetzee, Ph.D., Rachel Rapier, B.S., Nicole Odenwald, M.A., David Carreon, M.D., Jessica Hawkins, B.A., Maureen Chang, B.S., Jennifer Keller, Ph.D., Kristin Raj, M.D., Charles DeBattista, M.D., Booil Jo, Ph.D., Flint M. Espil, Ph.D., Alan F. Schatzberg, M.D., Keith D. Sudheimer, Ph.D., Nolan R. Williams, M.D
MDDEfficacy
April 2020
Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression
American Journal of Psychiatry | Volume 177, Issue 8
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Eleanor J. Cole, Ph.D., Katy H. Stimpson, B.S., Brandon S. Bentzley, M.D., Ph.D., Merve Gulser, B.S., Kirsten Cherian, Ph.D., Claudia Tischler, B.S., Romina Nejad, M.S., Heather Pankow, B.S., Elizabeth Choi, B.S., Haley Aaron, B.S., Flint M. Espil, Ph.D., Jaspreet Pannu, B.S., Xiaoqian Xiao, Ph.D., Dalton Duvio, B.S., Hugh B. Solvason, M.D., Jessica Hawkins, B.A., Austin Guerra, B.A., Booil Jo, Ph.D., Kristin S. Raj, M.D., Angela L. Phillips, Ph.D., Fahim Barmak, M.D., James H. Bishop, Ph.D., John P. Coetzee, Ph.D., Charles DeBattista, M.D., Jennifer Keller, Ph.D., Alan F. Schatzberg, M.D., Keith D. Sudheimer, Ph.D., Nolan R. Williams, M.D.
MDDOther
March 2020
Transcranial Magnetic Stimulation Parameter Space: Wide Open for Exploration
Biological Psychiatry | Volume 87, Issue 5, Pages 384-385
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Brandon S. Bentzley and Nolan R. Williams
MDDEfficacy
February 2018